Bernd Jilma Selected Research

thiamine triphosphorate (TTP)

2/2016	Caplacizumab for Acquired Thrombotic Thrombocytopenic Purpura.
4/2015	VWF excess and ADAMTS13 deficiency: a unifying pathomechanism linking inflammation to thrombosis in DIC, malaria, and TTP.
9/2011	A dose ranging phase I/II trial of the von Willebrand factor inhibiting aptamer ARC1779 in patients with congenital thrombotic thrombocytopenic purpura.
3/2011	Inhibition of von Willebrand factor by ARC1779 in patients with acute thrombotic thrombocytopenic purpura.
5/2010	The aptamer ARC1779 blocks von Willebrand factor-dependent platelet function in patients with thrombotic thrombocytopenic purpura ex vivo.
10/2009	Anti-von Willebrand factor aptamer ARC1779 for refractory thrombotic thrombocytopenic purpura.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Bernd Jilma Research Topics

Disease

49	Inflammation (Inflammations) 03/2023 - 02/2002
37	Endotoxemia 01/2022 - 05/2002
29	Hemorrhage 01/2022 - 12/2003
24	Thrombosis (Thrombus) 01/2023 - 11/2002
20	Sepsis (Septicemia) 11/2023 - 10/2002
19	Acute Coronary Syndrome 04/2023 - 10/2002
19	Myocardial Infarction 06/2022 - 09/2004
17	COVID-19 02/2024 - 10/2020
15	Autoimmune Hemolytic Anemia (Cold Agglutinin Disease) 03/2024 - 01/2019
14	Stroke (Strokes) 01/2023 - 04/2003
13	Infections 03/2023 - 02/2006
13	Cardiovascular Diseases (Cardiovascular Disease) 10/2022 - 10/2003
12	Disseminated Intravascular Coagulation 11/2023 - 05/2002
10	Hemolysis 03/2023 - 02/2003
9	Coronary Artery Disease (Coronary Atherosclerosis) 01/2023 - 01/2006
9	ST Elevation Myocardial Infarction 10/2022 - 06/2010
9	Critical Illness (Critically Ill) 01/2022 - 10/2002
9	Atherosclerosis 12/2020 - 09/2004
8	Anaphylaxis (Anaphylactic Shock) 11/2023 - 01/2019
8	Ischemic Stroke 01/2023 - 09/2004
8	Heart Arrest (Cardiac Arrest) 02/2022 - 03/2009
7	Neoplasms (Cancer) 01/2020 - 02/2006
7	Chronic Hepatitis C 01/2020 - 02/2006
7	Thrombocytopenia (Thrombopenia) 07/2016 - 10/2002
6	Out-of-Hospital Cardiac Arrest 09/2021 - 10/2018
6	Thrombotic Thrombocytopenic Purpura 04/2015 - 10/2009
5	Septic Shock (Toxic Shock Syndrome) 01/2024 - 12/2015
5	Fatigue 03/2023 - 01/2021
5	Body Weight (Weight, Body) 01/2023 - 01/2009
5	Unstable Angina 01/2022 - 03/2005
5	Mastocytosis 01/2022 - 01/2019
5	Birth Weight (Birth Weights) 01/2020 - 07/2006
4	Bacteremia 01/2020 - 10/2002
3	Vascular Diseases (Vascular Disease) 05/2023 - 04/2006
3	Liver Diseases (Liver Disease) 01/2023 - 02/2009
3	Hemophilia A (Haemophilia) 01/2023 - 03/2013
3	Hypothermia 02/2022 - 07/2009

Drug/Important Bio-Agent (IBA)

27	von Willebrand FactorIBA 02/2024 - 04/2004
16	TicagrelorIBA 01/2023 - 11/2010
14	EndotoxinsIBA 01/2023 - 02/2002
14	Interleukin-6 (Interleukin 6)IBA 12/2022 - 01/2004
14	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2022 - 04/2003
13	CytokinesIBA 01/2022 - 11/2002
13	C-Reactive ProteinIBA 09/2021 - 10/2006
13	Clopidogrel (Plavix)FDA Link 11/2020 - 04/2003
13	Thromboplastin (Tissue Factor)IBA 01/2020 - 05/2002
12	Biomarkers (Surrogate Marker)IBA 12/2022 - 09/2004
11	VaccinesIBA 12/2023 - 11/2008
11	sutimlimabIBA 03/2023 - 01/2019
11	Thrombin FDA Link 01/2020 - 09/2003
10	AnticoagulantsIBA 01/2022 - 05/2002
10	fibrin fragment D (D-dimer)IBA 12/2021 - 05/2002
9	Dacarbazine (DIC)FDA LinkGeneric 11/2023 - 01/2003
8	Hemoglobins (Hemoglobin)IBA 01/2023 - 10/2006
8	Proteins (Proteins, Gene)FDA Link 01/2021 - 11/2002
8	omega-Chloroacetophenone (Mace)IBA 01/2021 - 01/2011
8	ARC 1779IBA 08/2012 - 08/2009
7	Histamine (Histamine Dihydrochloride)FDA Link 04/2022 - 12/2015
7	Adenosine Diphosphate (ADP)IBA 01/2018 - 09/2004
6	Deamino Arginine Vasopressin (Desmopressin)FDA LinkGeneric 02/2024 - 03/2005
6	LipopolysaccharidesIBA 01/2023 - 02/2002
6	Fibrinogen (Factor I)FDA Link 12/2022 - 01/2007
6	EnzymesIBA 01/2022 - 11/2008
6	Prasugrel Hydrochloride FDA Link 01/2021 - 11/2012
6	FibrinIBA 01/2021 - 05/2002
6	CollagenIBA 01/2020 - 09/2004
6	AntigensIBA 01/2020 - 02/2006
6	thiamine triphosphorate (TTP)IBA 02/2016 - 10/2009
5	Complement C1s (C1 Esterase)IBA 03/2023 - 01/2019
5	BilirubinIBA 01/2023 - 02/2018
5	Complement System Proteins (Complement)IBA 01/2023 - 01/2019
5	Heparin (Liquaemin)FDA LinkGeneric 01/2022 - 10/2002
5	Morphine (MS Contin)FDA LinkGeneric 01/2022 - 02/2014
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2021 - 02/2002
5	AntibodiesIBA 11/2021 - 06/2006
5	Messenger RNA (mRNA)IBA 03/2017 - 09/2003
5	Glycoproteins (Glycoprotein)IBA 11/2016 - 02/2003
4	Erythropoietin FDA Link 03/2024 - 07/2006
4	MicroRNAs (MicroRNA)IBA 04/2023 - 03/2009
4	vasodilator-stimulated phosphoproteinIBA 01/2023 - 11/2008
4	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 10/2022 - 02/2010
4	2'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA 10/2022 - 01/2020
4	Amine Oxidase (Copper-Containing)IBA 04/2022 - 01/2018
4	TabletsIBA 01/2021 - 01/2015
4	Platelet Membrane Glycoprotein IIbIBA 11/2016 - 12/2003
3	SuperantigensIBA 01/2024 - 01/2016
3	Immunoglobulin G (IgG)IBA 03/2023 - 11/2008
3	Monoclonal AntibodiesIBA 01/2023 - 01/2022
3	Toll-Like Receptor 4IBA 01/2023 - 11/2005
3	ChemokinesIBA 12/2022 - 01/2008
3	Angiotensin IIIBA 11/2022 - 09/2004
3	Platelet Membrane GlycoproteinsIBA 01/2022 - 01/2020

Therapy/Procedure

33	Therapeutics 02/2024 - 10/2002
9	Percutaneous Coronary Intervention 12/2020 - 03/2005
6	Stents 04/2022 - 07/2013
5	Extracorporeal Membrane Oxygenation 02/2024 - 01/2021
5	Induced Hypothermia 02/2022 - 07/2009
4	Subcutaneous Injections 01/2023 - 01/2020
4	Heart-Assist Devices 11/2019 - 01/2009
3	Critical Care (Surgical Intensive Care) 02/2022 - 05/2016